Rheumatoid Arthritis – when your body declare war on itself !




As opposed to Osteoarthritis which is caused by wearing and tearing down cartilage in joints through a lifetime of use, Rheumatoid Arthritis is caused by an autoimmune response that causes the immune system to attack it’s own body.

There’s no cure and there’s no way of healing it since there’s no blood flow to the cartilage. if diagnosed early then Rheumatoid Arthritis can however be stoped or slowed down from progressing. However only 50% of treated patients will experience a reduction in disease activity. Since Rheumatoid Arthritis also carries and increased risk of cardio vascular diseases that number is way to low.

in the latest article I looked at Omega 3 as a natural way of reducing or even eliminate the pain from Arthritis – However a study published last year in JCI insight takes it a step further.

Because Omega 3 is a precursor to the prostaglandin ( a group of compounds with hormone like effect) group Specialized Proresolving Lipid Mediators (SPM) that decreases inflammation and inhibits the neutrophils that attacks the joints, these scientists decided to see if fish oil suppelements could raise SPM levels in patients with Rheumatoid Arthritis.

The trial did show an increase of the SPM Resolvin, along with significantly reduced joint inflammation to keep it short – the study more then implied that Rheumatoid Arthritis can be stoped by the use of a potent Omega 3 supplement.

Furthermore a study published in Annals of The Rheumatic Diseases on people who are genetically at risk of Rheumatoid Arthritis actually showed that fish oil plays a huge role in preventing rheumatoid Arthritis by regulating the number of antibodies that cause the disease.

These studies along with the knowledge we have on Omega 3 and pain relief makes it a must to be taking fishtail if you have Rheumatoid Arthritis.

Further Rading and source material:

Proresolving and cartilage-protective actions of resolvin D1 in inflammatory arthritis

Omega-3 fatty acids are associated with a lower prevalence of autoantibodies in shared epitope-positive subjects at risk for rheumatoid arthritis

What is arthritis – and what old school doctors are missing !




There’s actually more then 100 different types of Arthritis. We are not going through all of them today, but looking into the two most common types of Arthritis – Osteoarthritis and Rheumatoid Arthritis.

Osteoarthritis: In this condition you wear and tear the cartilage in the joints down. The cartilage in the joints absorb the shock from movements, and in the most critical cases it ends up being bone against bone, which is severely painful.

In the past Osteoarthritis was classified as non inflammatory Arthritis. However modern research has proven that to be a false. Unfortunately a lot of old school doctors who do not keep up with evolution is still saying non inflammatory Arthritis.

Osteoarthritis is caused by chronic inflammation in the joints. Chronic inflammation occurs when the body is not fed with enough anti inflammatory compounds to turn the acute inflammation off. Due to the inflammation the cartilage wears down as we use our joints, until there’s nothing or very little left.

Common symptoms of Osteoarthritis can be: deep aching pain, trouble getting dressed or combing your hair, difficulty with gripping things, problems with climbing stairs, stiffness after resting or sleeping, pain during movement, warm or swollen joints and inability to move through a full range og motion.

arthritis, joint pain

Rheumatoid Arthritis: on the other hand has always been categorized as inflammatory arthritis. Rheumatoid Arthritis is an autoimmune disease, where the body’s own immune system attacks the joints and cause inflammation.

There is however still confusion over why Rheumatoid Arthritis set off. There are those who believe that the immune system gets confused from an infection of virus or bacteria.

What we do know though is that the antibody Anti-Cyclic Citrulinated Peptide (anti-CCP) is present in most patients with Rheumatoid Arthritis. Along with a number of other blood tests and other diagnostic tools can anti-CCP be used to diagnose Rheumatoid Arthritis as well as estimate the severity of the disease.

Researchers has made the discovery that Rheumatoid patients who test positive for anti-CCP, have a common sequence of amino acids called the shared epitope, which is encoded into specific genetic markers – Human Leukocyte Antigens (HLA). The HLA is producing proteins that control immune responses. One theory is that the shared epitope could be responsible for creating the anti-CCP antibodies by attaching to these proteins.

So scientists really doesn’t know yet what’s causing Rheumatoid Arthritis. We know that there’s a genetic pre disposition to Rheumatoid Arthritis through anti-CCP and Rheumatoid Factor (RF) but most people suffering from Rheumatoid Arthritis doesn’t have a family history.

However knowing that in both cases of Arthritis inflammation plays a significant triggering role, then we get back to what I’ve been saying for years – that lifestyle and nutritional choices is a much bigger factor in our health then genetics.

If you hold that thought then let’s take a look at who’s in the highest risk group of getting Rheumatoid Arthritis:

  • Women is more likely to get Rheumatoid Arthritis then men
  • Overweight people are more prone to develop Rheumatoid Arthritis
  • If you smoke, you are more likely to develop Rheumatoid Arthritis and if you do, your symptoms are likely to be more severe
  • Rheumatoid Arthritis is more likely to appear at 40-60 years of age
  • If you are exposed to asbestos and Silica you are more likely to develop Rheumatoid Arthritis



  • Osteoarthritis
    All risk factors with the exception of gender, and partly but not solely age, is risk factors that blow chronic inflammation off the charts. Fat cells produce vast numbers of inflammatory compounds like their life depended on it ( and in a way it does) so overweight people are by definition highly inflamed. Smoking elevates inflammation like no other thing you could ever be exposed to, and environmental toxins are also a source of inflammation.

    All in all, there’s a puzzle that forms a pretty clear picture – Chronic inflammation is the trigger to both Osteoarthritis and Rheumatoid Arthritis – so making sure that your diet is anti inflammatory is not only the best way to prevent arthritis but also the best way to control it, if you already have it.

    Exit from darkness !




    Todays blog post is a bit different then what you are used to get from my hand. Acesalus.com usually place high emphasis on science and every article and every fragment of advice is based on what the science says or by questioning the validity of science, when it doesn’t add up.

    But today, as we – for now – puts closure to the theme on mental illness, I am going to do things quite differently. I am going to tell you my own personal story – with depression, completely striped down and naked.

    It’s my hope that I might be able to inspire someone out there to fight and overcome it, and if just one person finds inspiration and a better life then it’s been worth it.

    My story starts back in the year 2000. At the time I was franchising a 7-Eleven store, and I was at a place where although stressed and from time to time under huge pressure I felt that I could do anything in the world that I put my mind into. In a lot of ways, that was also what I did.

    However that year also set off my first depression, and started life events that would mark me for the rest of my life.

    What happened was that I was faced with 3 armed robberies that year – and as luck would have it, I was working all 3 times.

    First one didn’t bother me much really. It happened and I moved on. Six months later, I found myself looking into a gun barrel once more – and this time I felt the adrenaline rush through my veins differently then the first time, but again I brushed it off as a random event. Yet it shouldn’t be more random then the event reoccurring two weeks later but very differently.

    It was early morning, still dark, and I was actually having my back to the door while sorting that days delivery of news papers. I did not hear the door open, I didn’t hear his steps either, not a sound until I heard the sound of the gun hammer being pulled back. I have no idea how I was able to recognize the sound, but I instantly knew what was going on, and as I turned around I remember thinking “Shit, not again !”.


    But what I found when I turned was not even slightly close to what I had expected. At this point I was looking at a tall skinny person dressed completely in black, with exception of the white pattern of the skeleton on his face mask. If you remember the Scream movies that was popular at the time – that was exactly the mask he was wearing.

    He pointed the gun at me and ordered me to empty the cash register in his carry bag – I remember considering while doing it, wether or not I could in any way press the alarm without making a weird movement, and gave up on that idea while watching the gun point to my chest. Then at that point the most dreadful thing happened – as I was in the process, he said something to me, I’ve forgotten today what it was, but it made the blood in my veins freeze to ice, as I could recognize the voice. I could very distinctively recognize the voice, but something blocked me from placing a face to the voice.

    Now what really shook me around this last time was knowing that it was someone that I knew but not knowing who it was. Actually a few days after I had an idea who it was, but not knowing his name or being sure that it was him, it became a suspicion that I never said out loud. However seen in the backlight before the robbery he was at the store several times a week, after that incident I never saw him again – so maybe I was right after all.

    The experience was traumatic, and during the following months I asked 7-Eleven to arrange conversations with a counsellor. That however was denied, on the grounds that their counsellor service was only for employees not for franchisors. So rather then dealing with it I ended up on anxiety medication, frightened to be alone, and frightened to walk into my own store.

    It took me a year to get back on my feet and out of the medication. One of the tools to do this was letting go of the store and moving into a new environment.

    However medication or not, the trauma remained there and few years later, everything began to pop up again. This time I went to my doctor in the hope of being send to a counsellor, but given a 6 month waiting list for a counsellor he decided that it would be better to place me on medication. I was given Cipralex, at the time a pretty new drug used to treat depression.

    So over the next 6 months sudden anxiety attacks, dark and depressed thoughts was replaced with bad memory, low physical sensitivity, fatigue, and constant cognitive decline ( A few times I actually experienced to call the wrong person up and not realizing it until I was way into the conversation) , and a constant feeling of being “high” on something – as if I was there, but I was not.

    By allowing myself to rest, find my place in life and redefine my purpose and the support and love of a few select friends I managed to get off the medication and return to life.

    But it was not without a price. previously I had been known for having and elephants memory of even small details, but since taking the Cipralex I lost that extraordinary memory function and it has since taken years to retrain my brain up to normal memory function. On the physical side of things the sensitivity in my nerves and finer movement has suffered as well.

    The next years that follow I was in and out of depression, but whenever I was in it was always for limited times of 1-2 months and never with the agony of that first great depression, until the summer of 2016.

    That summer passed a lot of events on me. Primarily cut backs at my workplace of the time combined with a new leadership structure and a team spirit that was changed from “We stand together” to “Survival of the fittest” drew major strains on my mind control.

    When at the same time I had to let go of what I had at the time defined as my life purpose and highest passion – I fell completely to the floor, I was overwhelmed with fatigue, very dark and hopeless thoughts, as if life had no meaning and no joy.

    From there on it was like a freefall, I stoped my workouts (I used to be at the gym 4-5 times a week), I isolated myself as I had no energy for being social and if I had to be around people it would take me hours, and sometimes days, to work up the energy for that.

    As an attempt at overcoming the problem, I decided to change job, and getting into a new positive work environment did push me in the right direction. However it should not last very long, as at the same time I got in contact with a person who thrived on bullying, harassing and belittling me – unfortunately that contact was in a context where I couldn’t just walk away. I was back at working, sleeping and eating because that was all I had energy for.

    But that was also the time when sleeping failed me. I stoped being able to fall asleep and for the next 6 months I was sleeping 2-4 hours per day, after spending hours upon hours trying to fall asleep. If I was lucky then once a week my body would give up and sleep for 10-14 hours.

    It is obvious that this was not healthy in any way, neither physically or mentally, and as I look back at it now, I often wonder how I survived.

    The simple explanation to my survival is because I got sick and tired of feeling miserable. I started to rethink why I am here, what is my my purpose of being alive – and put it down on paper. One of those purpose defining things is actually this blog and the formation of a company devoted to promoting healthy life choices and natural alternatives to common health care.

    At the same time as I took this step, I started surrounding myself with people with a positive insight to life, and who could build me up through personal development.

    This was a life changer. I started to feel excitement sprout again. But I was still not getting regular sleep, fatigue was still after me like a demon in the night and though I was capable of smiling it never really hit the eyes.

    So how could I get the last bit of way ? I asked myself that question many times. Given what the antidepressants I was given years earlier ruined for me – that was one path that I knew I would never take again. But what then ?

    That was when I was introduced to a new supplement named VIVA. In my previous article I went through the science of Saffron as an antidpressant and anti anxiety remedy.

    Saffron was exactly what this supplement was based on – So with the knowledge of Saffron as a well studied remedy for better sleep, better mood and less anxiety I was excited to try it out.

    But what happened next impressed me more then any product had ever impressed me. The positive side of supplements is that they usually work better then pharmaceutical drugs on the long term – because they take care of the underlying root causes of disease, rather then just being a symptom treatment. They are usually also safer because they are simply food, but the downside is that most supplements takes time to work, and I have never seen a supplement that work faster then a pharmaceutical drug.

    So when I decided to test VIVA I took 2 tablets shortly before bedtime, and within half an hour I was sound asleep. I followed the procedure the following two nights with the same result. But whats further more is that I felt energetic at the point of waking up. On the 3rd and 4th day I also experienced radically enhanced mood levels. I was so impressed because not even pharmaceutical antidepressants work this fast.

    Today I’ve found a formula that works perfect for me – one tablet of VIVA in the morning to enhance my mood and two tablets 15 min. prior to bedtime for improved sleep.

    In my mind there’s no doubt that the main reason why we have ever increasing problems with mental illness is that our food today is deprived of nutrients like Omega 3 and antioxidants so that chronic inflammation in the brain causes levels of serotonin to fall, and by depriving us of the nutrients that’s supposed to give us fuel to cope with challenging events in life – simultaneously as we now soround ourselfs with more and more challenging lifestyles.

    If you want additional information on VIVA with Saffron then you can find it on this link or by clicking the image on the right. Also I would be happy to answer any questions you might have or go into more details with the process I went through – In that case you are welcome to send me a private message through my Facebook Page. All private messages remain that – private !

    Is pharmacology the solution to mood control ?




    In 2001 WHO ( The World Health Organisation) stated that around 450 million people suffered from some kind of mental or neurological condition. That translates to one in four people. This year WHO estimated that 300 million people are affected by depression alone.

    So why do we get so many people with mental disorders ?

    Since a study done at Boston Children’s Hospital confirmed that mental illness is caused by inflammation. Hence we know that nutrition plays an essential role.

    Studies has also made it 100% clear that there’s a clear link between stress and mental illness ( and depression in particular) – most likely this is because stress produces free radicals which again leads to inflammation.

    Pharmacology has never been more big business then it is today. Could an increased use of medicine in general be causing more and more people to suffer from mental problems ?

    Given our tagline “We question health” then at acesalus.com it’s impossible to look at these questions and not ask, is pharmacology the solution to mood control ?

    So let’s dig into it. When it comes to psychiatric treatment more and more doctors are asking these questions, some of them can be found in the documentary Making a killing: The untold story of psychotropic drugging, which you can watch below:

    But how good are the drugs that we use to treat these conditions ?

    Well Pfizer who manufacture Zoloft which is a top selling anti depressive drug, received a huge blow as they were sued for misleading marketing when they failed to publish trials that showed placebo to beat zoloft.

    Now the case was dismissed in court, however the fact remains that the trials where placebo beats Zoloft does exist and was excluded in the application for the drugs approval, which again leaves us with the question, how much can we trust the data from the studies where Zoloft showed better effect then placebo ?

    When asking the question of wether patients on antidepressants has benefit of the drugs, then we also need to look at what these drugs to to people’s life expectancy.

    What is very alarming is that the drugs used in psychiatric health care are very highly inflammatory by adding free radicals to your body. Wait ! , didn’t we start this article by saying that free radicals leads to inflammation, and inflammation leads to mental illness ? Yes ! we did, and that’s definitely cause for concern, but walks hand in hand with the fact that antidepressants have extensive side effects.

    So – do we die from antidepressants ? That question is not for me to answer, but a study by Petrascheck published in nature in 2007 concluded that the component Mianserin increased life expectancy by 20-33%. But what is pretty worrying is that the same study showed a decrease in life expectancy for substances: Fluoxitine (11-48% decrease), Sertraline ( 76-80% decrease) and Paroxetine (42-76% decrease). But what’s even worse is that as Kim Zarse and Michael Riston attempted to recreate Petraschack’s results, their findings was that Mianserin not only significantly decreased life expectancy but also elevated body fat.

    So if we have drugs with severe side effects, that most likely will kill you before time, and may not really help your mental issues – then we need to ask the question once again, is pharmacology the solution to mood control ?

    My personal opinion is no. Pharmacology might be the best bet that we have today, or maybe not the best bet, but the most researched and marketed bet we have today, but pharmacology does not cure the problem, which is malnutrition ( to many calories with to little nutrients), stress caused by the way our society is put together, polution etc. The drugs temporarily puts a lit on the symptoms.

    We need another paradigme !

    Further Reading:

    Antidepressants of the Serotonin-Antagonist Type Increase Body Fat and Decrease Lifespan of Adult Caenorhabditis elegans

    An antidepressant that extends lifespan in adult Caenorhabditis elegans

    Clinical trials on Zoloft vs. Placebo

    Whats new about the Mental Illness and inflammation link ?



    Yesterday I presented a study from the Boston Children’s Hospital that proved direct connection between mental illness and inflammation. This is not new, however the study is breaking news. So how does the study change the way we look at mental illness ?

    It’s been known for years now that chronic inflammation is the cause of about 90% of the lifestyle diseases that we carry around. Conditions such as acne, colitis, arthritis, any autoimmune disease, type II diabetes, obesity, Alzheimers, Parkinson, ADD/ADHD, Autism etc. has been either proven to be caused by inflammation or worsend by inflammation. Now there’s always been a lot of theory as to wether or not mental illness and inflammation might also go hand in hand – and most doctors who work independently from the pharmaceutical industry has pointed towards inflammation as the root cause of depression, anxiety disorders etc.

    In example watch this 8 minute presentation from Dr. Dave Scheiderer, about chronic inflammation and depression and why some people do not have full effect of modern medication.

    However the new thing that follows the study from Boston is that now we can actually prove that inflammation causes mental illness. The mentioned study used a mouse model with Lupus, that focused on interferon-alpha a protein cytokine that is released by white blood cells as an alarm response. Previously we’ve thought that Interferon – Alpha did not cross the blood – brain barrier but the new study showed that Interferon – Alpha did exactly that and caused changes in the brain and loss of brain synapses.

    This also validates reports saying that a diet of fish oil and high amount of antioxidants has helped people with non complex mental issues.

    This is highly interesting in the perspective of developing anti inflammatory mental treatments with no side effects.

    The study can be found here

    Inflammation linked to mental illness !



    Lupus is a chronic autoimmune disease that can damage skin, joints and/ or organs. When someone has Lupus then something goes wrong in the immune system , meaning that the body can’t recognize foreign invaders like bacteria and germs from it’s own healthy tissue and as a result the body starts attacking itself.

    lupus, symptoms, inflammation

    Up to 75% of those with Lupus develop neuropsychiatric symptoms. However we’ve been quite in the dark as to how Lupus affects the brain, until now. A new study from Boston Children’s Hospital thats been published in Nature has brought more clarification to the matter.

    Allison Bialas who worked on the study told to medical Express that in general people with Lupus show symptoms of anxiety, depression, headaches, seizures, even psychosis but it’s only recently been accepted as symptoms of Lupus.

    So much the more interesting the study. What they found was that in Lupus causes the body’s white blood celles to release type 1 interferon alpha, a cytokine that acts as an alarm signal and triggering a cascade of immune activity.

    Until now it has not been thought that these cytokines was able to cross into the brain – however the new study shows that is the case, and once there it launces microglia which is the immune defense of the Central Nervous System, which caused synapses to be lost in the frontal cortex.

    Now why is this study interesting ? Because the way the immune system works is to mark problems and dangers with inflammation, and as such Lupus has now become a model for hos mental illness is caused by an inflammatory response. Michael Caroll, senior author on the study concludes very clearly:”We’ve found a mechanism that directly links inflammation to mental illness,” .

    You can find the study by following this link.